Some days ago, the 2013 American College of Cardiology and the American Heart Association(ACC/AHA) Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adult was published*. Although a difficult subject, I find the Guideline accessible (as non-physician) and clear in its conclusions. The Big Three, Normal-Weight, Regular-Exercise & Non-Smoking, are foundation for arteriosclerotic cardiovascular disease(ASCVD) risk reduction efforts. And medical treatment is explained in Four Major Statin Benefit Groups. It’s clear that the strategy of High-intensity statin gains popularity, or better said: scientific proof. As an individual without clinical ASCVD or diabetes, I might have an estimated 10-year ASCVD risk of 7.5% or higher. If that’s the case, statins and I are a couple for the rest of my life. And my adherence to life style and medication regime is very important. Until now, the guidelines predict non-(medication)adherence if the LDL-C reduction is less than 50% from the untreated baseline (or something else causes this lack of success). I would suggest to implement a Medication Adherence Support System, especially because the person doesn’t feel sick and adherence plays such an important role in the results. And that result is to stay without any ASCVD events!
ACC/AHA Guideline* : http://circ.ahajournals.org/content/early/2013/11/11/01.cir.0000437738.63853.7a